Evaluation of safety and efficacy of an ophytrium and seboliance-containing mousse with or without shampoo in cats with keratinisation disorders

OBJECTIVES: This study aimed to assess the effectiveness of a protocol involving the application of topical products (DOUXO® S3 SEB Shampoo and Mousse; Ceva Santé Animale) containing ophytrium for managing feline keratinisation disorders. MATERIALS AND METHODS: Nineteen client-owned cats with a history of keratinisation disorders exhibited greasy or dry seborrhoea. Cats were treated with either a shampoo or mousse on day 0 (D0) and subsequently with the mousse every 48 to 72 hours for 3 weeks. Clinical signs were evaluated on D0, D7 and D21 using a modified Skin Seborrheic Index, which measured the percentage of body area affected, scaling, coat greasiness and secondary dermatological signs. Both veterinarians and owners provided subjective evaluations of overall skin condition and product efficacy. RESULTS: Of the 17 cats that completed the study, SSI scores improved significantly by D7 and D21, with reductions of ≥50% in 82.4% of cats. By D21, the affected body surface had decreased by 92.9%, scaling by 70.5% and greasiness by 68.3%. Veterinarians rated the improvement as satisfactory, good or excellent in 100% of cases. The protocol was deemed effective and practical by 100% and 88.2% of owners, respectively, with 94.1% declaring an improved condition of their cats' skin and coat. CLINICAL SIGNIFICANCE: The ophytrium-containing mousse and shampoo protocol was well tolerated and effective in significantly reducing seborrhoea in cats with keratinisation disorders. High satisfaction levels were reported by both veterinarians and owners, highlighting the protocol's efficacy and practicality.

Authors: C. Noli, H. Dropsy, A. Cozar, X. De Jaeger, R. Kesteman, A. Beck, R. Cristante, M. Debraine, F. Leymarios, A. Puozzo-Barichard and M. Gatellet Title: Evaluation of safety and efficacy of an ophytrium and seboliance-containing mousse with or without shampoo in cats with keratinisation disorders Full source: J Small Anim Pract, 2026,Vol 67, Iss 7, pp 619-626
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Abstract	Source
OBJECTIVES: This study aimed to assess the effectiveness of a protocol involving the application of topical products (DOUXO® S3 SEB Shampoo and Mousse; Ceva Santé Animale) containing ophytrium for managing feline keratinisation disorders. MATERIALS AND METHODS: Nineteen client-owned cats with a history of keratinisation disorders exhibited greasy or dry seborrhoea. Cats were treated with either a shampoo or mousse on day 0 (D0) and subsequently with the mousse every 48 to 72 hours for 3 weeks. Clinical signs were evaluated on D0, D7 and D21 using a modified Skin Seborrheic Index, which measured the percentage of body area affected, scaling, coat greasiness and secondary dermatological signs. Both veterinarians and owners provided subjective evaluations of overall skin condition and product efficacy. RESULTS: Of the 17 cats that completed the study, SSI scores improved significantly by D7 and D21, with reductions of ≥50% in 82.4% of cats. By D21, the affected body surface had decreased by 92.9%, scaling by 70.5% and greasiness by 68.3%. Veterinarians rated the improvement as satisfactory, good or excellent in 100% of cases. The protocol was deemed effective and practical by 100% and 88.2% of owners, respectively, with 94.1% declaring an improved condition of their cats' skin and coat. CLINICAL SIGNIFICANCE: The ophytrium-containing mousse and shampoo protocol was well tolerated and effective in significantly reducing seborrhoea in cats with keratinisation disorders. High satisfaction levels were reported by both veterinarians and owners, highlighting the protocol's efficacy and practicality.