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Authors: M. O. Dumitrache, A. L. Ursache, C. Toma, A. Negoescu, S. J. Rietmann, T. Leeb and M. C. Cadiergues
Title: Canine exfoliative cutaneous lupus erythematosus in two mixed breed littermates
Full source: Vet Dermatol, 2025,Vol 36, Iss 1, pp 99-103

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Abstract

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Canine exfoliative cutaneous lupus erythematosus (ECLE) is the rarest variant of cutaneous lupus in dogs and has strong breed predilections. This report presents the clinical, histopathological and immunohistochemical features of two ECLE cases in mixed breed littermates and confirms the expected genetic mutation. A therapeutic response to oclacitinib also is documented.